Motif ID: NFY{A,B,C}.p2

Z-value: 4.029


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409770920.572.0e-02Click!
NFYAchr6_+_411486910.533.6e-02Click!
NFYBchr12_-_103055924-0.204.5e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_48934831 3.359


chr19_+_19035792 3.251 NM_178526
SLC25A42
solute carrier family 25, member 42
chr14_+_23654161 2.905 DCAF11
DDB1 and CUL4 associated factor 11
chr14_-_73620826 2.903 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_+_23654307 2.898 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr2_+_69995740 2.801 MXD1
MAX dimerization protein 1
chr17_+_78009895 2.757 NARF
nuclear prelamin A recognition factor
chr17_+_54587882 2.676 PRR11
proline rich 11
chr17_+_78009819 2.576 NM_001083608
NM_012336
NM_031968
NARF


nuclear prelamin A recognition factor


chr2_-_239987629 2.556 HDAC4
histone deacetylase 4
chr19_+_63482118 2.479 NM_021089
ZNF8
zinc finger protein 8
chr1_-_109742020 2.478 NM_002959
SORT1
sortilin 1
chr3_+_187771139 2.447 NM_016306
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr3_+_187771192 2.446 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr14_+_23653848 2.268 DCAF11
DDB1 and CUL4 associated factor 11
chr20_-_45418818 2.260 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr2_+_203207912 2.254 FAM117B
family with sequence similarity 117, member B
chr1_+_42920683 2.241 YBX1
Y box binding protein 1
chr2_+_69995807 2.203 MXD1
MAX dimerization protein 1
chr14_+_103251798 2.132 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr17_+_73694992 2.129 NM_001010982
NM_001145526
AFMID

arylformamidase

chr17_+_34162525 2.107 NM_002795
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr2_-_73313823 2.072 NM_032319
C2orf7
chromosome 2 open reading frame 7
chr1_+_43888382 2.062 NM_014663
KDM4A
lysine (K)-specific demethylase 4A
chr2_+_26862416 2.056 CENPA
centromere protein A
chr1_-_39097904 2.041 NM_022157
RRAGC
Ras-related GTP binding C
chr1_+_43888415 2.017 KDM4A
lysine (K)-specific demethylase 4A
chr14_+_23653745 2.002 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr19_+_54962075 1.991 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr17_+_70256397 1.985 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr2_+_85676347 1.974 NM_016494
RNF181
ring finger protein 181
chr13_+_48916526 1.965 SETDB2
SET domain, bifurcated 2
chr2_+_69995656 1.956 NM_002357
MXD1
MAX dimerization protein 1
chr17_-_78249750 1.945 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr1_-_5975068 1.936 NM_015102
NPHP4
nephronophthisis 4
chr7_+_129497572 1.935 NM_014997
KLHDC10
kelch domain containing 10
chr2_-_96237665 1.934 STARD7
StAR-related lipid transfer (START) domain containing 7
chr7_+_129497808 1.924 KLHDC10
kelch domain containing 10
chr14_+_23653819 1.919 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_70256370 1.918 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_+_99974781 1.916 AGFG2
ArfGAP with FG repeats 2
chr2_-_96238296 1.905 NM_020151
STARD7
StAR-related lipid transfer (START) domain containing 7
chr1_-_148868713 1.904 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr16_-_57221235 1.901 CNOT1
CCR4-NOT transcription complex, subunit 1
chr2_-_234427884 1.894 HJURP
Holliday junction recognition protein
chr1_-_159257486 1.883 F11R
F11 receptor
chr9_-_37455429 1.875 ZBTB5
zinc finger and BTB domain containing 5
chr11_-_46824364 1.875 CKAP5
cytoskeleton associated protein 5
chr17_+_70256389 1.873 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_+_43373887 1.868 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr17_+_70256341 1.866 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr14_-_73620912 1.849 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr11_-_73371945 1.819 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_18700385 1.811 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr2_-_96238234 1.800 STARD7
StAR-related lipid transfer (START) domain containing 7
chr11_+_34416997 1.770 NM_001752
CAT
catalase
chr1_+_225194616 1.765 ADCK3
aarF domain containing kinase 3
chr7_+_129497637 1.745 KLHDC10
kelch domain containing 10
chr14_+_23008723 1.737 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr17_+_54587641 1.720 NM_018304
PRR11
proline rich 11
chr1_-_180627512 1.717 GLUL
glutamate-ammonia ligase
chr2_-_3360467 1.705 NM_003310
TSSC1
tumor suppressing subtransferable candidate 1
chr7_-_72114342 1.694 NM_001013739
STAG3L3
STAG3L2
STAG3L1
stromal antigen 3-like 3
stromal antigen 3-like 2
stromal antigen 3-like 1
chrX_-_77037563 1.691 NM_032121
MAGT1
magnesium transporter 1
chr3_-_187771025 1.684 NM_001134415
TBCCD1
TBCC domain containing 1
chr6_-_166716353 1.679 BRP44L
brain protein 44-like
chr19_-_2895894 1.678 NM_021217
ZNF77
zinc finger protein 77
chr1_-_148868178 1.677 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chr16_-_57221228 1.664 CNOT1
CCR4-NOT transcription complex, subunit 1
chr7_+_73944831 1.660 PMS2P5
postmeiotic segregation increased 2 pseudogene 5
chr1_-_5974997 1.647 NPHP4
nephronophthisis 4
chr2_-_234427921 1.647 NM_018410
HJURP
Holliday junction recognition protein
chrX_+_47999740 1.622 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr7_-_137337318 1.612 CREB3L2
cAMP responsive element binding protein 3-like 2
chr2_+_74914742 1.604 HK2
hexokinase 2
chr1_-_159257567 1.602 F11R
F11 receptor
chr1_+_148726497 1.597 TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr4_-_174492029 1.591 NM_001130688
NM_002129
HMGB2

high-mobility group box 2

chr16_-_57221240 1.590 NM_016284
NM_206999
CNOT1

CCR4-NOT transcription complex, subunit 1

chr11_+_63710206 1.567 STIP1
stress-induced-phosphoprotein 1
chr17_+_23670247 1.555 NM_014573
TMEM97
transmembrane protein 97
chr15_+_39412447 1.552 NUSAP1
nucleolar and spindle associated protein 1
chr1_-_148868644 1.552 ENSA
endosulfine alpha
chr1_+_148726537 1.550 NM_025150
TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr22_+_36384647 1.541 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr19_+_50086299 1.533 NM_001128916
NM_001128917
NM_006114
TOMM40


translocase of outer mitochondrial membrane 40 homolog (yeast)


chr7_+_6015423 1.523 AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr2_+_238540428 1.515 NM_080678
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr11_+_34417109 1.513 CAT
catalase
chrX_+_151750166 1.508 NM_001129765
NM_015922
NSDHL

NAD(P) dependent steroid dehydrogenase-like

chr7_+_99974720 1.496 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr11_+_63710242 1.495 STIP1
stress-induced-phosphoprotein 1
chr17_-_42012324 1.492 NM_001113738
NM_016632
NM_001039083
ARL17A

ARL17B
ADP-ribosylation factor-like 17A

ADP-ribosylation factor-like 17B
chr14_+_38714111 1.490 NM_002687
PNN
pinin, desmosome associated protein
chr3_-_42820950 1.488 NM_001099669
NM_014056
HIGD1A

HIG1 hypoxia inducible domain family, member 1A

chr5_+_145563305 1.470 RBM27
RNA binding motif protein 27
chr19_+_54160369 1.467 NM_000146
FTL
ferritin, light polypeptide
chr17_-_53950191 1.457 NM_004687
MTMR4
myotubularin related protein 4
chr1_-_219982049 1.448 DUSP10
dual specificity phosphatase 10
chr5_+_70918935 1.443 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr7_+_66405077 1.436 STAG3L4
stromal antigen 3-like 4
chr1_+_144149794 1.435 NM_006472
TXNIP
thioredoxin interacting protein
chr2_-_61618849 1.434 XPO1
exportin 1 (CRM1 homolog, yeast)
chr16_+_1772929 1.433 NM_012225
NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr15_-_18971400 1.431 HERC2P3
HERC2P2
hect domain and RLD 2 pseudogene 3
hect domain and RLD 2 pseudogene 2
chr1_+_12002138 1.431 MIIP
migration and invasion inhibitory protein
chr14_+_53933422 1.426 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr17_+_78009336 1.425 NM_001038618
NARF
nuclear prelamin A recognition factor
chr15_+_57184568 1.422 NM_004701
CCNB2
cyclin B2
chr19_+_46462125 1.417 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chrX_+_151750221 1.408 NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr6_-_31938530 1.405 NEU1
sialidase 1 (lysosomal sialidase)
chr7_-_99771429 1.404 PMS2P1
postmeiotic segregation increased 2 pseudogene 1
chr2_+_96237851 1.403 LOC285033
hypothetical protein LOC285033
chr10_+_62208094 1.400 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr6_-_31938572 1.394 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr2_+_47483795 1.386 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr1_+_43888391 1.375 KDM4A
lysine (K)-specific demethylase 4A
chr1_-_19101603 1.375 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr17_+_43082273 1.371 NM_002265
KPNB1
karyopherin (importin) beta 1
chr1_-_35795525 1.364 KIAA0319L
KIAA0319-like
chr13_-_100125028 1.361 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr12_+_53005177 1.360 NM_016057
COPZ1
coatomer protein complex, subunit zeta 1
chr17_-_41794825 1.356 NM_001039083
NM_001103154
ARL17A
ARL17B

ADP-ribosylation factor-like 17A
ADP-ribosylation factor-like 17B

chr2_+_203208064 1.351 NM_173511
FAM117B
family with sequence similarity 117, member B
chr5_+_70918893 1.350 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr6_+_43005214 1.349 CNPY3
canopy 3 homolog (zebrafish)
chr3_-_42820915 1.349 NM_001099668
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr16_-_88410523 1.342 NM_000135
NM_001018112
FANCA

Fanconi anemia, complementation group A

chr8_+_42129620 1.335 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr20_-_39680405 1.329 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr15_-_74390797 1.324 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr2_+_62786290 1.324 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr2_-_128501206 1.321 SAP130
Sin3A-associated protein, 130kDa
chr1_-_148868535 1.320 ENSA
endosulfine alpha
chr15_+_87919744 1.315 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr17_-_77411695 1.315 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr14_+_23711044 1.305 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr7_-_73944616 1.293 STAG3L2
stromal antigen 3-like 2
chrX_-_132947141 1.292 GPC3
glypican 3
chr19_+_12862966 1.291 NM_000159
NM_013976
GCDH

glutaryl-CoA dehydrogenase

chr5_+_70918888 1.289 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_+_238540361 1.288 UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr11_+_63710162 1.285 NM_006819
STIP1
stress-induced-phosphoprotein 1
chr9_-_127043436 1.282 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr16_+_15651583 1.281 NM_017668
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr17_+_44325127 1.276 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr6_+_160103500 1.275 ACAT2
acetyl-CoA acetyltransferase 2
chr1_+_28458546 1.270 NM_031459
SESN2
sestrin 2
chr7_+_98908451 1.266 ZNF789
zinc finger protein 789
chr2_+_47483750 1.256 NM_000251
MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr15_+_39310693 1.251 NM_007236
CHP
calcium binding protein P22
chr12_+_53005183 1.244 COPZ1
coatomer protein complex, subunit zeta 1
chr11_-_124486691 1.243 TMEM218
transmembrane protein 218
chr8_-_66708948 1.243 ARMC1
armadillo repeat containing 1
chr2_+_86521999 1.242 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr2_-_239987557 1.241 NM_006037
HDAC4
histone deacetylase 4
chr1_-_148936123 1.240 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr7_-_44854188 1.238 H2AFV
H2A histone family, member V
chr2_-_38683572 1.232 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr1_+_25629968 1.228 NM_018202
TMEM57
transmembrane protein 57
chr22_-_21193037 1.225 ZNF280B
zinc finger protein 280B
chr20_+_47096189 1.222 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr7_-_122130201 1.217 NM_198085
RNF148
ring finger protein 148
chr17_-_40380553 1.214 NM_001080443
KIF18B
kinesin family member 18B
chr20_-_48203570 1.212 TMEM189
transmembrane protein 189
chr12_+_53005192 1.206 COPZ1
coatomer protein complex, subunit zeta 1
chr11_-_62355128 1.205 STX5
syntaxin 5
chr9_-_94095734 1.205 IARS
isoleucyl-tRNA synthetase
chr15_-_26240844 1.204 NM_004667
HERC2P2
HERC2
hect domain and RLD 2 pseudogene 2
hect domain and RLD 2
chr14_+_23008742 1.203 NGDN
neuroguidin, EIF4E binding protein
chr4_-_84254873 1.201 PLAC8
placenta-specific 8
chr16_-_10943716 1.200 NM_014015
DEXI
Dexi homolog (mouse)
chr2_+_10180304 1.195 NM_001034
RRM2
ribonucleotide reductase M2
chr1_-_11245130 1.190 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr1_-_219982016 1.186 DUSP10
dual specificity phosphatase 10
chr22_+_22737753 1.183 NM_012295
CABIN1
calcineurin binding protein 1
chr9_-_35062545 1.182 VCP
valosin containing protein
chr10_+_104667991 1.181 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr11_-_62356094 1.178 NM_003164
STX5
syntaxin 5
chr17_+_43403405 1.176 NM_176096
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr2_-_61618898 1.173 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_-_35795592 1.172 NM_024874
KIAA0319L
KIAA0319-like
chr2_+_47483694 1.171 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr11_-_46824416 1.167 NM_001008938
NM_014756
CKAP5

cytoskeleton associated protein 5

chr9_-_127043169 1.163 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr1_-_219982081 1.162 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr9_-_37455250 1.161 ZBTB5
zinc finger and BTB domain containing 5
chr16_+_28869628 1.161 NM_032815
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr16_+_8675904 1.159 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr17_-_77411733 1.157 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr20_+_60744268 1.154 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr16_-_1601970 1.148 NM_014714
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr12_+_53005194 1.147 COPZ1
coatomer protein complex, subunit zeta 1
chr2_+_191453813 1.146 GLS
glutaminase
chr2_+_26862368 1.140 NM_001809
NM_001042426
CENPA

centromere protein A

chr11_-_67645433 1.139 NM_001277
NM_212469
CHKA

choline kinase alpha

chr20_+_47096280 1.135 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr20_+_60744231 1.134 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr22_+_22737870 1.132 CABIN1
calcineurin binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.59 3.64e-30 GO:0022403 cell cycle phase
2.22 2.72e-28 GO:0007049 cell cycle
2.68 5.44e-28 GO:0000278 mitotic cell cycle
2.37 3.75e-27 GO:0022402 cell cycle process
2.84 1.71e-24 GO:0000279 M phase
3.10 2.09e-21 GO:0000087 M phase of mitotic cell cycle
1.32 2.37e-20 GO:0044237 cellular metabolic process
1.78 6.96e-20 GO:0006996 organelle organization
3.02 2.93e-19 GO:0000280 nuclear division
3.02 2.93e-19 GO:0007067 mitosis
1.40 2.38e-18 GO:0044260 cellular macromolecule metabolic process
2.93 3.48e-18 GO:0048285 organelle fission
2.21 9.20e-16 GO:0051276 chromosome organization
1.45 2.19e-15 GO:0034641 cellular nitrogen compound metabolic process
1.56 6.13e-15 GO:0090304 nucleic acid metabolic process
1.27 1.21e-14 GO:0044238 primary metabolic process
1.43 3.59e-14 GO:0006807 nitrogen compound metabolic process
1.48 3.68e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 5.46e-14 GO:0008152 metabolic process
2.45 3.64e-12 GO:0051301 cell division
1.13 5.90e-12 GO:0009987 cellular process
3.77 9.18e-12 GO:0007059 chromosome segregation
2.40 3.97e-11 GO:0010564 regulation of cell cycle process
2.79 9.56e-11 GO:0000075 cell cycle checkpoint
2.47 1.17e-10 GO:0051325 interphase
1.44 1.61e-10 GO:0009058 biosynthetic process
2.73 1.81e-10 GO:0071156 regulation of cell cycle arrest
1.28 2.70e-10 GO:0043170 macromolecule metabolic process
1.42 3.58e-10 GO:0071842 cellular component organization at cellular level
3.94 3.94e-10 GO:0000236 mitotic prometaphase
1.44 4.08e-10 GO:0044249 cellular biosynthetic process
2.44 4.20e-10 GO:0051329 interphase of mitotic cell cycle
1.41 5.25e-10 GO:0071841 cellular component organization or biogenesis at cellular level
2.09 2.27e-09 GO:0006325 chromatin organization
1.79 3.53e-09 GO:0033554 cellular response to stress
1.95 5.53e-09 GO:0006259 DNA metabolic process
1.89 2.10e-08 GO:0051726 regulation of cell cycle
2.24 2.23e-08 GO:0006281 DNA repair
1.33 3.10e-08 GO:0016043 cellular component organization
1.97 6.09e-08 GO:0006974 response to DNA damage stimulus
1.32 6.85e-08 GO:0071840 cellular component organization or biogenesis
2.99 1.39e-07 GO:0006323 DNA packaging
2.82 1.50e-07 GO:0071103 DNA conformation change
2.87 3.88e-07 GO:0006333 chromatin assembly or disassembly
1.46 1.46e-06 GO:0034645 cellular macromolecule biosynthetic process
3.06 1.88e-06 GO:0065004 protein-DNA complex assembly
2.98 2.46e-06 GO:0071824 protein-DNA complex subunit organization
1.45 2.76e-06 GO:0009059 macromolecule biosynthetic process
2.77 3.28e-06 GO:0006310 DNA recombination
1.43 5.85e-06 GO:0016070 RNA metabolic process
1.42 6.43e-06 GO:0044281 small molecule metabolic process
4.81 1.82e-05 GO:0006695 cholesterol biosynthetic process
1.98 2.68e-05 GO:0016568 chromatin modification
1.33 3.96e-05 GO:0044267 cellular protein metabolic process
2.90 4.16e-05 GO:0034728 nucleosome organization
2.96 4.33e-05 GO:0031497 chromatin assembly
3.01 4.44e-05 GO:0006334 nucleosome assembly
2.49 6.42e-05 GO:0010498 proteasomal protein catabolic process
2.49 6.42e-05 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.95 1.47e-04 GO:0000819 sister chromatid segregation
2.49 3.08e-04 GO:0000082 G1/S transition of mitotic cell cycle
2.05 3.27e-04 GO:0007017 microtubule-based process
4.07 4.23e-04 GO:0016126 sterol biosynthetic process
1.25 4.85e-04 GO:0060255 regulation of macromolecule metabolic process
1.47 5.36e-04 GO:0044248 cellular catabolic process
1.86 7.75e-04 GO:0034622 cellular macromolecular complex assembly
1.23 9.10e-04 GO:0031323 regulation of cellular metabolic process
2.17 1.12e-03 GO:0006457 protein folding
1.76 1.33e-03 GO:0044262 cellular carbohydrate metabolic process
3.78 1.54e-03 GO:0000070 mitotic sister chromatid segregation
1.34 1.58e-03 GO:0010467 gene expression
2.83 1.67e-03 GO:0018196 peptidyl-asparagine modification
2.83 1.67e-03 GO:0018279 protein N-linked glycosylation via asparagine
1.21 1.71e-03 GO:0019222 regulation of metabolic process
2.57 2.22e-03 GO:0007126 meiosis
2.57 2.22e-03 GO:0051327 M phase of meiotic cell cycle
1.23 2.23e-03 GO:0080090 regulation of primary metabolic process
1.58 2.23e-03 GO:0065003 macromolecular complex assembly
2.55 2.75e-03 GO:0051321 meiotic cell cycle
2.29 2.89e-03 GO:0000226 microtubule cytoskeleton organization
2.88 3.15e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.41 3.44e-03 GO:0051641 cellular localization
2.17 3.75e-03 GO:0006260 DNA replication
1.31 6.17e-03 GO:0043412 macromolecule modification
1.67 6.42e-03 GO:0034621 cellular macromolecular complex subunit organization
2.64 6.92e-03 GO:0006487 protein N-linked glycosylation
1.58 9.09e-03 GO:0005975 carbohydrate metabolic process
1.63 1.10e-02 GO:0044265 cellular macromolecule catabolic process
1.98 1.19e-02 GO:0051186 cofactor metabolic process
1.27 1.20e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.49 1.28e-02 GO:0043933 macromolecular complex subunit organization
7.27 1.34e-02 GO:0002566 somatic diversification of immune receptors via somatic mutation
7.27 1.34e-02 GO:0016446 somatic hypermutation of immunoglobulin genes
2.40 2.21e-02 GO:0000086 G2/M transition of mitotic cell cycle
1.45 2.22e-02 GO:0055114 oxidation-reduction process
1.24 2.48e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.51 2.57e-02 GO:0006082 organic acid metabolic process
2.38 2.67e-02 GO:0051320 S phase
1.54 2.79e-02 GO:0006396 RNA processing
1.27 2.82e-02 GO:0006355 regulation of transcription, DNA-dependent
1.30 2.84e-02 GO:0006464 protein modification process
1.35 2.93e-02 GO:0009056 catabolic process
1.78 2.93e-02 GO:0019941 modification-dependent protein catabolic process
1.76 2.95e-02 GO:0044257 cellular protein catabolic process
1.79 3.23e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.77 3.26e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.77 3.60e-02 GO:0043632 modification-dependent macromolecule catabolic process
4.01 3.64e-02 GO:0006271 DNA strand elongation involved in DNA replication
4.67 3.67e-02 GO:0006298 mismatch repair
2.26 3.86e-02 GO:0007093 mitotic cell cycle checkpoint
1.50 4.02e-02 GO:0042180 cellular ketone metabolic process
1.24 4.04e-02 GO:0010468 regulation of gene expression
1.54 4.33e-02 GO:0009057 macromolecule catabolic process
1.50 4.38e-02 GO:0019752 carboxylic acid metabolic process
1.50 4.38e-02 GO:0043436 oxoacid metabolic process
2.95 4.56e-02 GO:0000910 cytokinesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.28 7.68e-70 GO:0044424 intracellular part
1.26 2.53e-66 GO:0005622 intracellular
1.34 2.23e-65 GO:0043229 intracellular organelle
1.39 9.15e-65 GO:0043231 intracellular membrane-bounded organelle
1.34 9.51e-65 GO:0043226 organelle
1.39 2.09e-64 GO:0043227 membrane-bounded organelle
1.51 3.96e-47 GO:0005634 nucleus
1.50 7.07e-46 GO:0044446 intracellular organelle part
1.50 2.84e-45 GO:0044422 organelle part
1.84 2.98e-36 GO:0070013 intracellular organelle lumen
1.80 1.80e-34 GO:0043233 organelle lumen
1.79 3.65e-34 GO:0031974 membrane-enclosed lumen
1.79 4.83e-31 GO:0044428 nuclear part
1.27 1.38e-27 GO:0005737 cytoplasm
2.64 2.71e-27 GO:0005694 chromosome
1.81 1.48e-26 GO:0031981 nuclear lumen
2.64 1.43e-22 GO:0044427 chromosomal part
1.46 1.15e-19 GO:0032991 macromolecular complex
1.31 3.99e-19 GO:0044444 cytoplasmic part
1.80 3.81e-18 GO:0005654 nucleoplasm
1.51 1.08e-17 GO:0043228 non-membrane-bounded organelle
1.51 1.08e-17 GO:0043232 intracellular non-membrane-bounded organelle
1.44 9.33e-15 GO:0043234 protein complex
2.73 2.18e-12 GO:0000785 chromatin
3.27 6.77e-12 GO:0000793 condensed chromosome
3.20 1.74e-11 GO:0000775 chromosome, centromeric region
2.76 1.98e-11 GO:0000228 nuclear chromosome
1.91 4.71e-11 GO:0015630 microtubule cytoskeleton
2.91 1.27e-10 GO:0044454 nuclear chromosome part
1.06 3.88e-10 GO:0044464 cell part
1.06 4.09e-10 GO:0005623 cell
1.85 1.13e-09 GO:0044429 mitochondrial part
1.54 2.35e-08 GO:0005739 mitochondrion
1.75 6.37e-08 GO:0031967 organelle envelope
1.41 7.53e-08 GO:0005829 cytosol
4.08 2.01e-07 GO:0000794 condensed nuclear chromosome
1.72 2.05e-07 GO:0031975 envelope
2.53 2.65e-07 GO:0005819 spindle
3.47 3.19e-07 GO:0000779 condensed chromosome, centromeric region
3.26 5.43e-07 GO:0000776 kinetochore
1.70 8.86e-07 GO:0044451 nucleoplasm part
3.33 6.94e-06 GO:0000777 condensed chromosome kinetochore
2.12 1.29e-05 GO:0005759 mitochondrial matrix
1.97 8.71e-05 GO:0005874 microtubule
3.21 1.02e-04 GO:0000922 spindle pole
1.72 2.29e-04 GO:0005740 mitochondrial envelope
7.48 3.12e-04 GO:0008250 oligosaccharyltransferase complex
2.70 3.15e-04 GO:0032993 protein-DNA complex
3.17 4.43e-04 GO:0000786 nucleosome
2.04 5.52e-04 GO:0016604 nuclear body
3.02 5.97e-04 GO:0034399 nuclear periphery
6.80 1.04e-03 GO:0000780 condensed nuclear chromosome, centromeric region
1.64 1.63e-03 GO:0005730 nucleolus
1.67 2.06e-03 GO:0031966 mitochondrial membrane
2.50 2.51e-03 GO:0005741 mitochondrial outer membrane
6.23 2.82e-03 GO:0032300 mismatch repair complex
1.28 3.21e-03 GO:0031090 organelle membrane
1.39 6.33e-03 GO:0044430 cytoskeletal part
2.86 7.62e-03 GO:0016363 nuclear matrix
1.86 7.72e-03 GO:0005635 nuclear envelope
1.90 7.88e-03 GO:0005813 centrosome
1.31 1.08e-02 GO:0012505 endomembrane system
2.24 1.14e-02 GO:0031968 organelle outer membrane
2.51 1.73e-02 GO:0000790 nuclear chromatin
2.17 2.17e-02 GO:0019867 outer membrane
1.30 2.41e-02 GO:0005856 cytoskeleton
2.84 2.42e-02 GO:0016605 PML body
7.79 3.81e-02 GO:0032389 MutLalpha complex
1.42 3.85e-02 GO:0044432 endoplasmic reticulum part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 4.88e-20 GO:0005488 binding
1.26 1.79e-18 GO:0005515 protein binding
1.37 1.53e-11 GO:0003676 nucleic acid binding
1.41 4.03e-09 GO:0003677 DNA binding
1.20 2.16e-06 GO:0003824 catalytic activity
1.32 4.98e-05 GO:0000166 nucleotide binding
1.36 7.48e-04 GO:0030554 adenyl nucleotide binding
1.36 8.44e-04 GO:0005524 ATP binding
1.36 1.13e-03 GO:0032559 adenyl ribonucleotide binding
1.53 1.34e-03 GO:0019899 enzyme binding
6.01 1.66e-03 GO:0030983 mismatched DNA binding
7.27 3.57e-03 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
1.30 4.57e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.29 5.80e-03 GO:0017076 purine nucleotide binding
8.01 7.20e-03 GO:0032404 mismatch repair complex binding
1.29 7.62e-03 GO:0032553 ribonucleotide binding
1.29 7.62e-03 GO:0032555 purine ribonucleotide binding
6.54 1.08e-02 GO:0004576 oligosaccharyl transferase activity
2.86 1.16e-02 GO:0019902 phosphatase binding
1.24 1.76e-02 GO:0046914 transition metal ion binding
1.83 1.84e-02 GO:0048037 cofactor binding
1.44 2.05e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.26 2.82e-02 GO:0008270 zinc ion binding
3.19 4.01e-02 GO:0003678 DNA helicase activity
1.42 4.29e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.43 4.65e-02 GO:0017111 nucleoside-triphosphatase activity